Colloquium" DNA in a tight squeeze: The physics of viral infection and gene regulation", by Dr. Jane' Kondev, Physics Department, Brandeis University

Science / Technology - Colloquium

Wednesday, October 26, 2005
5:00 PM-6:00 PM

Olin Hall
107

DNA in cells and viruses finds itself packed into a tight space, occupying a volume much smaller that the volume it adopts free in solution. This state of confinement places important constraints on a variety of biological processes, such as viral infection, gene expression, and DNA recombination. Quantitative experimental techniques such as laser tweezers, cryo-electron microscopy and fluorescence microscopy have recently begun to probe the confined state of DNA, both in live cells and in the test tube. In this talk I will describe this emerging experimental landscape and outline the theoretical challenges it poses. The particular examples I will focus on will be provided by DNA packing in viruses and gene regulation in bacteria where physics models can be used to propose a new generation of quantitative biology experiments.

Cost: FREE

Suggested Audiences: College

E-mail: garcia@wpi.edu
Phone: 508-831-5342

Last Modified: October 21, 2005 at 11:25 AM

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