Physic Department Colloquium, "Optical Biopsy: detecting cancer and pre-cancer with elastic light scattering spectroscopy," by Irving J. Bigio, Boston University, Departments of Biomedical Engineering, ECE, Physics and School of Medicine Monday, 10/6/2014, 4:00 PM-5:00 PM
Optical spectroscopy mediated by fiberoptic probes can be used to perform noninvasive, or minimally-invasive, real-time assessment of tissue pathology in-situ. The method of elastic-scattering spectroscopy (ESS) is sensitive to the sub-cellular architectural changes, such as nuclear grade and nuclear to cytoplasm ratio, mitochondrial size and density, etc., which correlate with features used by pathologists when performing histological assessment to detect disease. The ESS method senses those morphology changes without actually imaging the microscopic structure. Clinical demonstrations of ESS have been conducted in a variety of organ sites, with promising results; larger-scale clinical studies are now ongoing. Refreshments will be served at 3:30 P.M. in Olin Hall 118 Sponsored by: WPI Physics Department

WPI Physics Department Colloquium, "THz Spectroscopy: Studying Carrier Dynamics and Solar Energy Conversion in Nanostructured Materials and Progress Toward THz VCD," by Dr. Charles Schmuttenmaer, Yale University, Department of Chemistry Monday, 10/13/2014, 4:00 PM-5:00 PM
Terahertz spectroscopy has proven itself to be an excellent non-contact probe of charge injection and conductivity with sub-picosecond time resolution. One may exploit this capability to study a variety of materials, and here we choose to probe the transient photoconductivity of dye-sensitized nanostructured wide band gap semiconductors photosensitized by high oxidation-potential chromophores. These systems are of interest in the area of renewable energy research and artificial photosynthesis. I will also describe recent efforts, both experimental and computational, to probe and understand low frequency vibrational modes in organic molecular crystals. Calculating these modes has proven challenging because of the large influence of weak van der Waals interactions which are difficult to treat computationally for periodic systems, i.e., crystals. In addition, efforts toward measuring vibrational circular dichroism (VCD) in the far-infrared will be reported. Refreshments will be served in Olin Hall 118 at 3:30 P.M. Sponsored by: WPI Physics Department

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