Math Bio Seminar Series-Maryann Hohn (University of Connecticut)-Partial Differential Equation Models and Numerical Simulations of RNA Interactions

Mathematics - Lecture/Discussion

Tuesday, October 1, 2013
4:00 PM-5:00 PM

Stratton Hall

ABSTRACT: Our genetic information is stored in our cells via DNA that is transcribed into a single chain of nucleotides called RNA which is then translated into proteins. New discoveries of other non-coding macromolecules such as microRNA (miRNA) found that these macromolecules regulate developmental events through certain interactions with messenger RNA (mRNA). By binding to specific sites on a strand of mRNA, miRNA may cause a gene to be activated or suppressed, turning a gene ``on" or ``off." To understand these interactions, a mathematical model was developed that consists of a system of coupled partial differential equations describing mRNA and miRNA interactions across cells and tissue. In this talk, we will discuss the mathematical models created and the numerical methods used to solve these equations.

Suggested Audiences: Adult, College


Last Modified: September 17, 2013 at 5:15 PM